Entry ID | Original Release date | Data summary | Entry Title | Citation Title | Authors |
---|---|---|---|---|---|
31107 | 2023-10-18 | Chemical Shifts: 1 set |
Solution NMR structure of KaiB variant from Thermosynechococcus elongatus vestitus (KaiBTV-4) |
Predicting multiple conformations via sequence clustering and AlphaFold2
|
Adedolapo M Ojoawo, D Kern, Hannah Wayment-Steele, Julia Apitz, Lucy Colwell, M Homberger, Renee Otten, Sergey Ovchinnikov, Warintra Pitsawong |
52017 | 2023-11-28 | Chemical Shifts: 1 set |
KaiBRS-3m |
Predicting multiple conformations via sequence clustering and AlphaFold2
|
Adedolapo M Ojoawo, D Kern, Hannah Wayment-Steele, Julia Apitz, Lucy Colwell, M Homberger, Renee Otten, Sergey Ovchinnikov, Warintra Pitsawong |
52018 | 2023-11-28 | Chemical Shifts: 2 sets |
Backbone 1H, 13C, and 15N chemical shift assignments of the ground state and the fold-switched state of KaiB-RS |
Predicting multiple conformations via sequence clustering and AlphaFold2
|
Adedolapo M Ojoawo, D Kern, Hannah Wayment-Steele, Julia Apitz, Lucy Colwell, M Homberger, Renee Otten, Sergey Ovchinnikov, Warintra Pitsawong |
52019 | 2024-09-27 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N chemical shift assignments of the fold-switched state of KaiB-TV |
Predicting multiple conformations via sequence clustering and AlphaFold2
|
Adedolapo M Ojoawo, D Kern, Hannah Wayment-Steele, Julia Apitz, Lucy Colwell, M Homberger, Renee Otten, Sergey Ovchinnikov, Warintra Pitsawong |
51232 | 2022-03-09 | Chemical Shifts: 1 set |
Geobacillus stearothermophilus Adenylate Kinase with Zinc |
Structure determination of high-energy states in a dynamic protein ensemble
|
Daniel Haussinger, Dorothee Kern, Douglas L Theobald, John B Stiller, Pascal S Rieder, Renee Otten |
51233 | 2022-03-09 | Chemical Shifts: 1 set |
Geobacillus stearothermophilus Adenylate Kinase with Cobalt |
Structure determination of high-energy states in a dynamic protein ensemble
|
Daniel Haussinger, Dorothee Kern, Douglas L Theobald, John B Stiller, Pascal S Rieder, Renee Otten |
50471 | 2020-12-28 | Chemical Shifts: 1 set |
Backbone 1H, 15N, and 13C Chemical Shift Assignments for the Apo-State of Kemp Eliminase HG3.17 |
How directed evolution reshapes energy landscapes to boost catalysis
|
Aina E Cohen, Donald Hilvert, Dorothee Kern, H Adrian Bunzel, MacKenzie Patterson, Renee Otten, Ricardo AP Padua, Sarah L Perry, Shuo Sui, Vy Nguyen, Warintra Pitsawong |
27520 | 2018-11-16 | Chemical Shifts: 1 set Spectral_peak_list: 4 sets |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for SHP2 (1-529) |
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
|
Dorothee Kern, Ingrid Marko, John B Stiller, Renee Otten, Ricardo AP Padua, Warintra Pitsawong, Yizhi Sun |
27522 | 2018-11-16 | Chemical Shifts: 1 set Spectral_peak_list: 3 sets |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for the tandem-SH2 domain of SHP2 (1-217) with a point mutation E76K |
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
|
Dorothee Kern, Ingrid Marko, John B Stiller, Renee Otten, Ricardo AP Padua, Warintra Pitsawong, Yizhi Sun |
27521 | 2018-11-16 | Chemical Shifts: 1 set Spectral_peak_list: 4 sets |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for the phosphatase domain of SHP2 (216-529) |
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
|
Dorothee Kern, Ingrid Marko, John B Stiller, Renee Otten, Ricardo AP Padua, Warintra Pitsawong, Yizhi Sun |
27217 | 2018-04-18 | Chemical Shifts: 2 sets |
Backbone Chemical Shift Assignments for the S99T/C115S Mutant of Human Cyclophilin A |
Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution
|
Dan S Tawfik, David Mavor, Dorothee Kern, James S Fraser, Lillian R Kenner, Lin Liu, Michael W Clarkson, Renee Otten |
27218 | 2018-04-18 | Chemical Shifts: 2 sets |
Backbone Chemical Shift Assignments for the S99T/C115S/I97V Mutant of Human Cyclophilin A |
Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution
|
Dan S Tawfik, David Mavor, Dorothee Kern, James S Fraser, Lillian R Kenner, Lin Liu, Michael W Clarkson, Renee Otten |
34123 | 2017-10-31 | Chemical Shifts: 1 set |
Solution structure of Drosophila melanogaster Loquacious dsRBD2 |
Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD / Dcr-2 complex in RNA interference
|
A Geerlof, C Hartlmuller, C Kreutz, C Wunderlich, JN Tants, K Foerstemann, M Juen, M Sattler, O Lange, R Boettcher, R Stehle, S Fesser, S Kunzelmann, T Kern |
34124 | 2017-10-31 | Chemical Shifts: 1 set |
Solution structure of Drosophila melanogaster Loquacious dsRBD1 |
Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD / Dcr-2 complex in RNA interference
|
A Geerlof, C Kreutz, C Wunderlich, JN Tants, K Foerstemann, M Sattler, O Lange, R Boettcher, R Stehle, S Fesser, S Kunzelmann, T Kern |
25125 | 2015-06-29 | Chemical Shifts: 1 set |
Solution Structure and Chemical Shift Assignments for the Apo form of the Receiver Domain of Nitrogen Regulatory Protein C ( NTRC ) at 35C |
Free energy landscape of activation in a signalling protein at atomic resolution
|
Dimitar V Pachov, Dorothee Kern, Francesco Pontiggia, Janice Villali, Michael F Hagan, Michael W Clarkson, Vijay V Pande |
25124 | 2015-06-29 | Chemical Shifts: 1 set |
Solution Structure and Chemical Shift Assignments for BeF3 activated Receiver Domain of Nitrogen Regulatory Protein C ( NtrC ) at 35C |
Free energy landscape of activation in a signalling protein at atomic resolution
|
Dimitar V Pachov, Dorothee Kern, Francesco Pontiggia, Janice Villali, Michael F Hagan, Michael W Clarkson, Vijay V Pande |
19092 | 2014-12-18 | Chemical Shifts: 1 set |
Backbone 1H, 15N Chemical Shift Assignments for R156K mutant Escherichia coli Adenylate Kinase with 20mM ADP at 293K |
Catalytic Strategies used by Kinases in Phosphoryl-Transfer Reactions
|
Dimitr V Pachov, Dorothee Kern, Francesco Pontiggia, Lien A Phung, Michael F Hagan, Padraig N Murphy, Renee Otten, Roman V Agafonov, S Jordan J Kerns, Vu Thai, Young-Jin Cho |
19093 | 2014-12-18 | Chemical Shifts: 1 set |
Backbone 1H, 15N Chemical Shift Assignments for R156K mutant Escherichia coli Adenylate Kinase with 20mM ADP and magnesium at 293K |
Catalytic Strategies used by Kinases in Phosphoryl-Transfer Reactions
|
Dimitr V Pachov, Dorothee Kern, Francesco Pontiggia, Lien A Phung, Michael F Hagan, Padraig N Murphy, Renee Otten, Roman V Agafonov, S Jordan J Kerns, Vu Thai, Young-Jin Cho |
19091 | 2014-12-18 | Chemical Shifts: 1 set |
Backbone 1H, 15N Chemical Shift Assignments for wild-type Escherichia coli Adenylate Kinase with 20mM ADP and Magnesium at 298K |
Catalytic Strategies used by Kinases in Phosphoryl-Transfer Reactions
|
Dimitr V Pachov, Dorothee Kern, Francesco Pontiggia, Lien A Phung, Michael F Hagan, Padraig N Murphy, Renee Otten, Roman V Agafonov, S Jordan J Kerns, Vu Thai, Young-Jin Cho |
19090 | 2014-12-18 | Chemical Shifts: 1 set |
Backbone 1H, 15N Chemical Shift Assignments for wild-type Escherichia coli Adenylate Kinase with 20mM ADP and Calcium at 298K |
Catalytic Strategies used by Kinases in Phosphoryl-Transfer Reactions
|
Dimitr V Pachov, Dorothee Kern, Francesco Pontiggia, Lien A Phung, Michael F Hagan, Padraig N Murphy, Renee Otten, Roman V Agafonov, S Jordan J Kerns, Vu Thai, Young-Jin Cho |
19089 | 2014-12-18 | Chemical Shifts: 4 sets |
Backbone 1H, 15N Chemical Shift Assignments for wild-type Escherichia coli Adenylate Kinase with 20mM ADP at 293, 298, 303, and 313K |
Catalytic Strategies used by Kinases in Phosphoryl-Transfer Reactions
|
Dimitr V Pachov, Dorothee Kern, Francesco Pontiggia, Lien A Phung, Michael F Hagan, Padraig N Murphy, Renee Otten, Roman V Agafonov, S Jordan J Kerns, Vu Thai, Young-Jin Cho |
18808 | 2013-01-28 | Chemical Shifts: 2 sets |
Structure, phosphorylation and U2AF65 binding of the Nterminal domain of splicing factor 1 during 3 splice site recognition |
Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition
|
Angela Kraemer, Hyun-Seo Kang, Ivona Bagdiul, Michael Sattler, Nina Maeusbacher, Peijian Zou, Stephan Sieber, Thomas Kern, Tobias Madl, Yun Zhang |
18802 | 2013-01-28 | Chemical Shifts: 1 set |
Structure, phosphorylation and U2AF65 binding of the Nterminal domain of splicing factor 1 during 3 splice site recognition |
Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition
|
Angela Kraemer, Hyun-Seo Kang, Ivona Bagdiul, Michael Sattler, Nina Maeusbacher, Peijian Zou, Stephan Sieber, Thomas Kern, Tobias Madl, Yun Zhang |
18711 | 2013-06-10 | Chemical Shifts: 1 set |
TBA |
TBA
|
J Peschek, M Graewert, M Groll, R Mueller, Thomas Kern, T Madl |
17218 | 2010-11-10 | Chemical Rates: 1 set |
Enzyme Dynamics During Catalysis |
Enzyme Dynamics During Catalysis
|
Daryl A Bosco, Dorothee Kern, Elan Z Eisenmesser, Mikael Akke |
5899 | 2003-10-06 | Chemical Shifts: 1 set |
NMR Solution Structure of BeF3-Activated Spo0F, 20 conformers |
The NMR Solution Structure of BeF(3)(-)-activated Spo0F Reveals the Conformational Switch in a Phosphorelay System
|
A K Gardino, B F Volkman, D E Wemmer, D Kern, H S Cho, S Y Lee |
4763 | 2002-04-11 | Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 2 sets |
15N relaxation data and model-free parameters for the N-terminal receiver domain of double-mutant (D86N/A89T) unphosphorylated NtrC receiver domain (NtrCr(D86N/A89T)) |
Two-state allosteric behavior in a single domain signaling protein
|
Brian F Volkman, David E Wemmer, Doron Lipson, Dorothee Kern |
4762 | 2002-04-11 | Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 2 sets |
15N relaxation data and model-free parameters for the N-terminal receiver domain of wild-type unphosphorylated NtrC receiver domain (NtrCr) |
Two-state allosteric behavior in a single domain signaling protein
|
Brian F Volkman, David E Wemmer, Doron Lipson, Dorothee Kern |
4527 | 2000-06-16 | Chemical Shifts: 1 set |
1H, 13C, and 15N Chemical Shift Assignments for the N-terminal receiver domain of NtrC (unphosphorylated) |
Structure of a Transiently Phosphorylated "Switch" in Bacterial Signal Transduction
|
B F Volkman, D E Wemmer, Dorothee Kern, M J Nohaile, P Luginbuhl, S Kustu |
4528 | 2000-06-16 | Chemical Shifts: 1 set |
1H, 13C, and 15N Chemical Shift Assignments for the N-terminal receiver domain of NtrC (phosphorylated) |
Structure of a Transiently Phosphorylated "Switch" in Bacterial Signal Transduction
|
B F Volkman, D E Wemmer, D Kern, M J Nohaile, P Luginbuhl, S Kustu |
4330 | 2005-01-21 | Chemical Shifts: 1 set |
A Single-Chain T Cell Receptor |
Structure, Specificity and CDR Mobility of a Class II Restricted T Cell Receptor.
|
B J Hare, D F Wyss, E L Reinherz, G Wagner, M S Osburne, P S Kern |
4097 | 1999-01-25 | Chemical Shifts: 1 set |
Backbone 1H, 13C and 15N Chemical Shift Assignment for the HIV-1 RNase H Domain |
Characterization of a Folding Intermediate from HIV-1 Ribonuclease H
|
Kern Gunther, Susan Marqusee, Tracy M Handel |