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Entry ID	Original Release date	Data summary	Entry Title	Citation Title	Authors
52669	2025-01-31	Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set	FUS LCRGG1 dispersed phase 1H-15N backbone relaxation	Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation.	Jeetain Mittal, Nicolas L Fawzi, Noah Wake, Shuo-Lin L Weng, Szu-Huan H Wang, Tongyin Zheng, Valentin Kirilenko
52653	2025-01-31	Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set	Backbone 1H, 15N relaxation of FUS LC-RGG1 condensed phase	Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation.	Jeetain Mittal, Nicolas L Fawzi, Noah Wake, Shuo-Lin L Weng, Szu-Huan H Wang, Tongyin Zheng, Valentin Kirilenko
52284	2024-02-13	Chemical Shifts: 1 set	Efg1 C-PrLD assignments	Structure and interactions of prion-like domains in transcription factor Efg1 phase separation	Nicolas L Fawzi, Szu-Huan Wang, Tongyin Zheng
52258	2024-02-13	Chemical Shifts: 1 set	Efg1 N prion-like domain assignments	Structure and interactions of prion-like domains in transcription factor Efg1 phase separation	Nicolas L Fawzi, Szu-Huan Wang, Tongyin Zheng
52061	2023-10-28	Chemical Shifts: 1 set	Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 6F to A	A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain	Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty
52062	2023-10-28	Chemical Shifts: 1 set	Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A outside CR	A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain	Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty
52060	2023-10-28	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A inside CR	A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain	Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty
51069	2021-09-19	Chemical Shifts: 1 set	FUS RGG3 (453-507)	Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads	Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang
51068	2021-09-19	Chemical Shifts: 1 set	FUS RGG2 (372-422)	Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads	Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang
51067	2021-09-19	Chemical Shifts: 1 set	FUS RGG1 (164-267)	Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads	Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang
50766	2021-03-03	Chemical Shifts: 2 sets	Backbone resonance assignments of LINE-1 retrotransposable element ORF1 protein N-terminal region.	Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain.	Eileen L Murphy, Gerwald Jogl, Grace Y Li, Jocelyn C Newton, John M Sedivy, Mandar T Naik, Nicolas L Fawzi
50708	2021-02-22	Chemical Shifts: 1 set	N-terminal acetylated FUS LC (1-163)	N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma	Anastasia Murthy, Anna Bock, Frank Shewmaker, Jeetain Mittal, Nicolas Fawzi, Nina Jovic, WaiShing Tang
50314	2022-04-13	Chemical Shifts: 1 set	FtsZ CTD (317-383)	An enhancer sequence in the intrinsically disordered region of FtsZ promotes polymer-guided substrate processing by ClpXP protease	Botai Xuan, Carolina M Pena, Catherine Trebino, Christopher J LaBreck, Jodi L Camberg, Kaylee L Mathews, Marissa G Viola, Negar Rahmani, Nicolas L Fawzi, Theodora M Perdikari, XienYu Chua
50258	2020-12-07	Chemical Shifts: 2 sets	ch-TOG 1-250	Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration	Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan
50254	2020-08-20	Chemical Shifts: 1 set	hnRNPA2 1-189	Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation	Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Vendetti
50255	2020-08-20	Chemical Shifts: 1 set	hnRNPA2 1-189 310K	Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation	Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Venditti
50257	2020-08-20	Chemical Shifts: 1 set	hnRNPA2 1-189 bound to rA2RE11	Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid-liquid phase separation and aggregation	Balabhadra Khatiwada, Joshua Amaya, Mandar Naik, Nicolas Fawzi, Scott Watters, Veronica Ryan, Vincenzo Vendetti
50189	2020-12-07	Chemical Shifts: 1 set	hnRNPF prion-like domain 365-415 backbone and Cbeta chemical shifts	Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration	Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan
50090	2020-02-21	Chemical Shifts: 1 set	G335D TDP43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27887	2019-06-11	Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set	Backbone (1H and 15N) Chemical Shift Assignments and Relaxation Parameters for the low complexity domain of FUS in the condensed phase	Molecular interactions underlying liquid-liquid phase separation of the FUS low complexity domain	Anastasia Murthy, Gregory Dignon, Gul Zerze, Jeetain Mittal, Nicolas Fawzi, Sapun Parekh, Yelena Kan
27788	2019-10-30	Chemical Shifts: 1 set	G335N TDP-43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27790	2019-10-30	Chemical Shifts: 1 set	G338A TDP-43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27789	2019-10-30	Chemical Shifts: 1 set	G335S TDP-43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27750	2019-10-30	Chemical Shifts: 1 set	G335A TDP-43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27751	2019-10-30	Chemical Shifts: 1 set	G335N TDP-43_267-414	TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function	Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala
27649	2018-11-05	Chemical Shifts: 1 set	hnRNPA2 low complexity domain 266-341 backbone and Cbeta chemical shifts	The SH3 domain of Fyn kinase interacts with and induces liquid-liquid phase separation of the low-complexity domain of hnRNPA2	Joshua Amaya, Nicolas Fawzi, Veronica Ryan
27299	2018-01-11	Chemical Shifts: 1 set	hnRNPA2 P298L low complexity domain 190-341 backbone and Cbeta chemical shifts	Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation	Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
30345	2018-02-21	Chemical Shifts: 2 sets	Solution structure of TDP-43 N-terminal domain dimer.	A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation and RNA splicing	Ailin Wang, Alexander E Conicella, Amanda Nourse, Ashley N Reeb, Daniel Ramirez Montero, Erik W Martin, Frank Shewmaker, Hermann Broder B Schmidt, Mandar T Naik, Nicolas L Fawzi, Rajat Rohatgi, Shannon N Rhoads, Tanja Mittag, Veronica H Ryan, Yuna M Ayala
27124	2018-01-11	Chemical Shifts: 1 set	hnRNPA2 D290V low complexity domain 190-341 backbone and Cbeta chemical shifts	Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation	Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
27123	2018-01-11	Chemical Shifts: 1 set	hnRNPA2 low complexity domain 190-341 backbone and Cbeta chemical shifts	Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation	Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan
27125	2017-08-02	Chemical Shifts: 1 set	FUS low complexity domain with 12 phosphomimetic S/T to E mutations	Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity	Abigail M Janke, Alexander E Conicella, Frank Shewmaker, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Robert B Best, Robert N Cole, Robert O'Meally, Shannon N Rhoads, Veronica H Ryan, Wenwei Zheng, Zachary Monahan
27063	2017-10-04	Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set	Degenerate heptads 27-52 of human RNA polymerase II C-terminal domain (DNA-directed RNA polymerase II subunit RPB1): assignments and backbone relaxation	Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment	Abigail M Janke, Alexander E Conicella, Dahee Seo, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Vahid Rahmanian
26828	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant A326P	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26826	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321G	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26827	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321V	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26831	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant M337P	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26830	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant M337V	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26829	2016-08-19	Chemical Shifts: 1 set	Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant Q331K	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26823	2016-08-19	Chemical Shifts: 2 sets Coupling Constants: 1 set Heteronuclear NOE Values: 2 sets T1 Relaxation Values: 2 sets T2 Relaxation Values: 2 sets	Backbone 1H, 13C, and 15N Chemical Shift Assignments, HNHA scalar coupling, and 15N backbone relaxation data for TDP-43 C-terminal domain wild type	ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain	Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi
26672	2015-10-09	Chemical Shifts: 1 set	Backbone 1H, 13C (C, CA, CB), and 15N Chemical Shift Assignments for the low complexity prion-like domain of Fused in Sarcoma (FUS 1-163)	Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II	Abigail M Janke, Christy L Rhine, Kathleen A Burke, Nicolas L Fawzi