Entry ID | Original Release date | Data summary | Entry Title | Citation Title | Authors |
---|---|---|---|---|---|
52913 | 2025-04-02 | Chemical Shifts: 16 sets |
Backbone (1H and 15N) Chemical Shift Perturbations of Fused in Sarcoma Low-Complexity Domain in different 2.5%w/v and 5%w/v solutions of Alkanediols |
Molecular insights into the effect of hexanediol on FUS phase separation
|
Anastasia C Murthy, Jeetain Mittal, Nicolas L Fawzi, Noah Wake, Shuo-Lin Weng, Theodora M Perdikari, Tongyin Zheng |
52669 | 2025-01-31 | Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
FUS LCRGG1 dispersed phase 1H-15N backbone relaxation |
Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation.
|
Jeetain Mittal, Nicolas L Fawzi, Noah Wake, Shuo-Lin L Weng, Szu-Huan H Wang, Tongyin Zheng, Valentin Kirilenko |
52653 | 2025-01-31 | Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
Backbone 1H, 15N relaxation of FUS LC-RGG1 condensed phase |
Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation.
|
Jeetain Mittal, Nicolas L Fawzi, Noah Wake, Shuo-Lin L Weng, Szu-Huan H Wang, Tongyin Zheng, Valentin Kirilenko |
52586 | 2024-11-15 | Chemical Shifts: 1 set |
Histone H4 Tail with Uniform Lysine Acetylation |
Acetylation-Dependent Compaction of the Histone H4 Tail Ensemble
|
Emma J Kraft, Jeetain Mittal, Scott A Showalter, Sophia M Dewing, Tien M Phan |
52585 | 2024-11-15 | Chemical Shifts: 1 set |
Histone H4 tail |
Acetylation-Dependent Compaction of the Histone H4 Tail Ensemble
|
Emma J Kraft, Jeetain Mittal, Scott A Showalter, Sophia M Dewing, Tien M Phan |
52061 | 2023-10-28 | Chemical Shifts: 1 set |
Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 6F to A |
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain
|
Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
52062 | 2023-10-28 | Chemical Shifts: 1 set |
Backbone 1H and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A outside CR |
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain
|
Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
52060 | 2023-10-28 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for the region 310-350 for TDP-43 C-terminal domain engineered variant 5M to A inside CR |
A synergy between site-specific and transient interactions drives the phase separation of a disordered, low-complexity domain
|
Azamat Rizuan, Jayakrishna Shenoy Krishnashenoy Padmabai, Jeetain Mittal, Jose F Mercado Ortiz, Nicolas L Fawzi, Priyesh Mohanty |
51512 | 2023-06-30 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N chemical shift assignments for the chromoshadow domain (residue 112-176) of human heterochromatin protein 1a (HP1a). |
Molecular interactions underlying the phase separation of HP1a: role of phosphorylation, ligand and nucleic acid binding
|
Azamat Rizuan, Bryce E Ackermann, Cheenou Her, Galia T Debelouchina, Jeetain Mittal, Nina Jovic, Tien M Phan, Utkarsh Kapoor, Young Kim |
51068 | 2021-09-19 | Chemical Shifts: 1 set |
FUS RGG2 (372-422) |
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
|
Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
51069 | 2021-09-19 | Chemical Shifts: 1 set |
FUS RGG3 (453-507) |
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
|
Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
51067 | 2021-09-19 | Chemical Shifts: 1 set |
FUS RGG1 (164-267) |
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
|
Abigail M Janke, Anastasia C Murthy, Da Hee H Seo, Jeetain Mittal, Nicolas L Fawzi, Nina Jovic, Theodora Myrto M Perdikari, Wai Shing S Tang |
50708 | 2021-02-22 | Chemical Shifts: 1 set |
N-terminal acetylated FUS LC (1-163) |
N-terminal acetylation modestly enhances phase separation and reduces aggregation of the low-complexity domain of RNA-binding protein fused in sarcoma
|
Anastasia Murthy, Anna Bock, Frank Shewmaker, Jeetain Mittal, Nicolas Fawzi, Nina Jovic, WaiShing Tang |
50258 | 2020-12-07 | Chemical Shifts: 2 sets |
ch-TOG 1-250 |
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
|
Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan |
50189 | 2020-12-07 | Chemical Shifts: 1 set |
hnRNPF prion-like domain 365-415 backbone and Cbeta chemical shifts |
Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration
|
Anne Hart, Camillo Saueressig, Gregory Dignon, Jeetain Mittal, Jeremy Lins, Mandar Naik, Nicolas Fawzi, Theodora Perdikari, Veronica Ryan |
50090 | 2020-02-21 | Chemical Shifts: 1 set |
G335D TDP43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27887 | 2019-06-11 | Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
Backbone (1H and 15N) Chemical Shift Assignments and Relaxation Parameters for the low complexity domain of FUS in the condensed phase |
Molecular interactions underlying liquid-liquid phase separation of the FUS low complexity domain
|
Anastasia Murthy, Gregory Dignon, Gul Zerze, Jeetain Mittal, Nicolas Fawzi, Sapun Parekh, Yelena Kan |
27790 | 2019-10-30 | Chemical Shifts: 1 set |
G338A TDP-43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27789 | 2019-10-30 | Chemical Shifts: 1 set |
G335S TDP-43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27788 | 2019-10-30 | Chemical Shifts: 1 set |
G335N TDP-43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27751 | 2019-10-30 | Chemical Shifts: 1 set |
G335N TDP-43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27750 | 2019-10-30 | Chemical Shifts: 1 set |
G335A TDP-43_267-414 |
TDP-43 alpha-helical structure tunes liquid-liquid phase separation and function
|
Alexander E Conicella, Alexandra M D'Ordine, Gregory L Dignon, Gul H Zerze, Hermann Broder B Schmidt, Jeetain Mittal, Nicolas L Fawzi, Rajat Rohatgi, Young C Kim, Yuna M Ayala |
27299 | 2018-01-11 | Chemical Shifts: 1 set |
hnRNPA2 P298L low complexity domain 190-341 backbone and Cbeta chemical shifts |
Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation
|
Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
27123 | 2018-01-11 | Chemical Shifts: 1 set |
hnRNPA2 low complexity domain 190-341 backbone and Cbeta chemical shifts |
Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation
|
Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
27125 | 2017-08-02 | Chemical Shifts: 1 set |
FUS low complexity domain with 12 phosphomimetic S/T to E mutations |
Phosphorylation of the FUS low-complexity domain disrupts phase separation, aggregation, and toxicity
|
Abigail M Janke, Alexander E Conicella, Frank Shewmaker, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Robert B Best, Robert N Cole, Robert O'Meally, Shannon N Rhoads, Veronica H Ryan, Wenwei Zheng, Zachary Monahan |
27124 | 2018-01-11 | Chemical Shifts: 1 set |
hnRNPA2 D290V low complexity domain 190-341 backbone and Cbeta chemical shifts |
Disease mutation, protein interactions, and posttranslational modifications modulate hnRNPA2 liquid-liquid phase separation
|
Alexander E Conicella, Charlene V Chabata, Gregory L Dignon, Gul H Zerze, Jeetain Mittal, Joshua Amaya, Kathleen A Burke, Nicolas L Fawzi, Rute Silva, Veronica H Ryan |
27063 | 2017-10-04 | Chemical Shifts: 1 set Heteronuclear NOE Values: 1 set T1 Relaxation Values: 1 set T2 Relaxation Values: 1 set |
Degenerate heptads 27-52 of human RNA polymerase II C-terminal domain (DNA-directed RNA polymerase II subunit RPB1): assignments and backbone relaxation |
Lysines in RNA polymerase II C-terminal domain contribute to TAF15 fibril recruitment
|
Abigail M Janke, Alexander E Conicella, Dahee Seo, Jeetain Mittal, Kathleen A Burke, Nicolas L Fawzi, Vahid Rahmanian |
26826 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321G |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26831 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant M337P |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26830 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant M337V |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26829 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant Q331K |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26828 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain engineered variant A326P |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26827 | 2016-08-19 | Chemical Shifts: 1 set |
Backbone 1H, 13C, and 15N Chemical Shift Assignments for TDP-43 C-terminal domain ALS-associated variant A321V |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |
26823 | 2016-08-19 | Chemical Shifts: 2 sets Coupling Constants: 1 set Heteronuclear NOE Values: 2 sets T1 Relaxation Values: 2 sets T2 Relaxation Values: 2 sets |
Backbone 1H, 13C, and 15N Chemical Shift Assignments, HNHA scalar coupling, and 15N backbone relaxation data for TDP-43 C-terminal domain wild type |
ALS Mutations Disrupt Phase Separation Mediated by alpha-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
|
Alexander E Conicella, Gul H Zerze, Jeetain Mittal, Nicolas L Fawzi |