Entry ID | Original Release date | Data summary | Entry Title | Citation Title | Authors |
---|---|---|---|---|---|
25810 | 2016-07-20 | Chemical Shifts: 1 set |
NMR structure of the N-domain of troponin C bound to the switch region of troponin I and the covalent levosimendan analog i9. |
Troponin C with covalently bound levosimendan analog i9 enhances contraction in cardiac muscle fibers
|
Brian D Sykes, Ian M Robertson, Malcolm Irving, Sandra E Pineda Sanabria, Yin-Biao Sun |
25511 | 2016-06-30 | Chemical Shifts: 1 set T1 Relaxation Values: 2 sets T2 Relaxation Values: 2 sets |
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C |
Structure and Dynamics of the Acidosis-Resistant A162H Mutant of the Switch Region of Troponin I Bound to the Regulatory Domain of Troponin C
|
Brian D Sykes, Ian M Robertson, Sandra E Pineda Sanabria |
25495 | 2015-06-01 | Chemical Shifts: 1 set |
Structure and dynamics of the acidosis-resistant a162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C |
Structure and dynamics of the acidosis-resistant A162H mutant of the switch region of troponin I bound to the regulatory domain of troponin C
|
Brian D Sykes, Ian M Robertson, Sandra E Pineda Sanabria |
19816 | 2014-03-10 | Chemical Shifts: 1 set |
NMR structure of the C-domain of troponin C bound to the anchoring region of troponin I |
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
|
Brian D Sykes, Ian M Robertson, Olga K Baryshnikova, Pascal Mercier |
19817 | 2014-03-10 | Chemical Shifts: 1 set |
NMR structure of the dilated cardiomyopathy mutation G159D in troponin C bound to the anchoring region of troponin I |
The dilated cardiomyopathy G159D mutation in cardiac troponin C weakens the anchoring interaction with troponin I.
|
Brian D Sykes, Ian M Robertson, Olga K Baryshnikova, Pascal Mercier |
19789 | 2014-02-11 | Chemical Shifts: 2 sets |
N domain of cardiac troponin C bound to the switch fragment of fast skeletal troponin I at pH 6 |
Conformation of the critical pH sensitive region of troponin depends upon a single residue in troponin I.
|
Brian D Sykes, Ian M Robertson, Peter C Holmes, Sandra E Pineda-Sanabria |
17440 | 2011-02-24 | Chemical Shifts: 1 set |
Structure of trans-Resveratrol in complex with the cardiac regulatory protein Troponin C |
Structure of trans-Resveratrol in Complex with the Cardiac Regulatory Protein Troponin C.
|
Brian D Sykes, Ian M Robertson, Sandra E Pineda-Sanabria |
17243 | 2011-06-01 | Chemical Shifts: 1 set |
The Solution Structure of Human Cardiac Troponin C in complex with the Green Tea Polyphenol; (-)-epigallocatechin-3-gallate |
Solution structure of human cardiac troponin C in complex with the green tea polyphenol, (-)-epigallocatechin 3-gallate.
|
Brian D Sykes, Ian M Robertson, Monica X Li |
17103 | 2010-09-08 | Chemical Shifts: 1 set |
The structure of the calcium-sensitizer, dfbp-o, in complex with the N-domain of troponin C and the switch region of troponin I |
A structural and functional perspective into the mechanism of Ca(2+)-sensitizers that target the cardiac troponin complex.
|
Brian D Sykes, Ian M Robertson, Monica X Li, Yin-Biao Sun |