| Entry ID |
Original Release date |
Data summary |
Entry Title |
Citation Title |
Authors |
| 53129 |
2025-10-08 |
: sets
|
The clinical drug candidate anle138b binds predominantly to a central cavity in lipidic Ab40 fibrils and modulates fibril formation. |
Anle138b binds predominantly to the central cavity in lipidic A\u03b2\u2084\u2080 fibrils and modulates fibril formation
|
Andrei Leonov, Armin Giese, Benedikt Frieg, Bert L de Groot, Christian Dienemann, Christian Griesinger, Dietmar Riedel, Dirk Matthes, Evgeny Nimerovsky, Gunnar F Schroder, Kai Xue, Karin Giller, Kerstin Overkamp, Loren B Andreas, Marianna Stampolaki, Mookyoung Han, Sergey Ryazanov, Stefan Becker |
| 52006 |
2024-02-14 |
Chemical Shifts: 1 set
|
Assignment of Lipidic amyloid-b (1-40) fibril |
Cryo-EM structures of lipidic fibrils of amyloid-b (1-40)
|
Benedikt Frieg, Christian Dienemann, Christian Griesinger, Dietmar Riedel, Gunnar F Schroeder, Karin Giller, Loren B Andreas, Mookyoung Han, Stefan Becker |
| 51584 |
2023-05-10 |
Chemical Shifts: 1 set
|
Backbone 13C and 15N Chemical Shift Assignments for fibrillar Amyloid Beta (1-42) at pH 7.0 |
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Ab(1-42) Amyloid Fibrils
|
Benedikt Frieg, Dieter Willbold, Henrike Heise, Holger Gohlke, Lothar Gremer, Luis Gardon, Nina Becker, Patrick Freiburg, Philipp Neudecker, Tatsiana Kupreichyk |
| 51497 |
2022-10-11 |
Chemical Shifts: 1 set
|
Nervy homology 2 domain (NHR2) from AML-ETO |
Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
|
Aldino Viegas, Benedikt Frieg, David Bickel, Georg Groth, Holger Gohlke, Jens Reiners, Julia Przibilla, Luitgard Nagel-Steger, Manuela Mayer, Manuel Etzkorn, Mohanraj Gopalswamy, Sander Smits, Shahina Akter, Stephan Schott-Verdugo, Thomas Pauly, Tobias Kroeger |
| 51321 |
2023-05-10 |
Chemical Shifts: 1 set
|
Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) in 28% Acetonitrile at pH 2.0 |
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Ab(1-42) Amyloid Fibrils
|
Benedikt Frieg, Daniel Scholzel, Dieter Willbold, Henrike Heise, Holger Gohlke, Lothar Gremer, Nina Becker, Patrick G Meckelburg, Philipp Neudecker, Tatsiana Kupreichyk |
| 51323 |
2023-05-10 |
Chemical Shifts: 1 set
|
Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) at pH 2.0 |
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Ab(1-42) Amyloid Fibrils
|
Benedikt Frieg, Daniel Scholzel, Dieter Willbold, Henrike Heise, Holger Gohlke, Lothar Gremer, Nina Becker, Patrick G Meckelburg, Philipp Neudecker, Tatsiana Kupreichyk |
| 51322 |
2023-05-10 |
Chemical Shifts: 1 set
|
Sequence-specific Backbone Resonance Assignments of Human Amyloid-beta(1-42) at pH 7.0 |
Atomic Resolution Insights into pH Shift Induced Deprotonation Events in LS-Shaped Ab(1-42) Amyloid Fibrils
|
Benedikt Frieg, Daniel Scholzel, Dieter Willbold, Henrike Heise, Holger Gohlke, Lothar Gremer, Nina Becker, Patrick G Meckelburg, Philipp Neudecker, Tatsiana Kupreichyk |
