BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 6537

Title: Small Molecule Ligand Induces Nucleotide Flipping in (CAG)n Trinucleotide Repeats   PubMed: 16407992

Authors: Nakatani, Kazuhiko; Hagihara, Shinya; Goto, Yuki; Kobori, Akio; Hagihara, Masaki; Hayashi, Gosuke; Kyo, Motoki; Nomura, Makoto; Mishima, Masaki; Kojima, Chojiro

Citation: Nakatani, Kazuhiko; Hagihara, Shinya; Goto, Yuki; Kobori, Akio; Hagihara, Masaki; Hayashi, Gosuke; Kyo, Motoki; Nomura, Makoto; Mishima, Masaki; Kojima, Chojiro. "Small-molecule ligand induces nucleotide flipping in (CAG)(n) trinucleotide repeats."  Nat. Chem. Biol. 1, 39-43 (2005).

Assembly members:
5'-d(CTAACAGAATG)-3', polymer, 11 residues, Formula weight is not available
5'-d(CATTCAGTTAG)-3', polymer, 11 residues, Formula weight is not available
NAZ, non-polymer, 459.500 Da.

Natural source:   Common Name: Synthesis   Taxonomy ID: not available   Superkingdom: Other   Kingdom: Not applicable   Genus/species: Synthesis Synthesis

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
5'-d(CTAACAGAATG)-3': CTAACAGAATG
5'-d(CATTCAGTTAG)-3': CATTCAGTTAG

Data sets:
Data typeCount
1H chemical shifts196

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
15'-d(CTAACAGAATG)-3'1
25'-d(CATTCAGTTAG)-3'2
3Naphthyridine-Azaquinolone, 13
4Naphthyridine-Azaquinolone, 23

Entities:

Entity 1, 5'-d(CTAACAGAATG)-3' 11 residues - Formula weight is not available

1   DCDTDADADCDADGDADADT
2   DG

Entity 2, 5'-d(CATTCAGTTAG)-3' 11 residues - Formula weight is not available

1   DCDADTDTDCDADGDTDTDA
2   DG

Entity 3, Naphthyridine-Azaquinolone, 1 - C24 H25 N7 O3 - 459.500 Da.

1   NAZ