BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 17580

Title: Myc G-quadruplex formed at the 5'-end of NHEIII element   PubMed: 21795379

Authors: Mathad, Raveendra; Hatzakis, Emmanuel; Yang, Danzhou

Citation: Mathad, Raveendra; Hatzakis, Emmanuel; Dai, Jixun; Yang, Danzhou. "c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability."  Nucleic Acids Res. 39, 9023-9033 (2011).

Assembly members:
DNA_G-quadruplex, polymer, 19 residues, 510.438 Da.

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: chemical synthesis   Host organism: Escherichia coli

Entity Sequences (FASTA):
DNA_G-quadruplex: TAGGGAGGGTAGGGAGGGT

Data sets:
Data typeCount
1H chemical shifts161

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Myc G-quadruplex1

Entities:

Entity 1, Myc G-quadruplex 19 residues - 510.438 Da.

1   DTDADGDGDGDADGDGDGDT
2   DADGDGDGDADGDGDGDT

Samples:

sample_1: DNA G-quadruplex 1 mM; H20 90%; D2O 10%%

sample_conditions_1: ionic strength: 100 mM; pH: 7.0; pressure: 1 atm; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

X-PLOR NIH, Brunger - refinement

NMR spectrometers:

  • Bruker Avance 600 MHz

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