BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 7244

Title: 1H, 15N, 13C', 13CA and 13CB Chemical Shift Assignments of intrinsically disordered gamma-synuclein   PubMed: 17088319

Authors: Marsh, Joseph; Singh, Vinay; Zongchao, Jia; Forman-Kay, Julie

Citation: Marsh, Joseph; Singh, Vinay; Zongchao, Jia; Forman-Kay, Julie. "Sensitivity of secondary structure propensities to sequence differences between a- and g-synuclein: Implications for fibrillation"  Protein Sci. 15, 2795-2804 (2006).

Assembly members:
gamma-synuclein, polymer, 127 residues, Formula weight is not available

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
gamma-synuclein: MDVFKKGFSIAKEGVVGAVE KTKQGVTEAAEKTKEGVMYV GAKTKENVVQSVTSVAEKTK EQANAVSEAVVSSVNTVATK TVEEAENIAVTSGVVRKEDL RPSAPQQEGEASKEKEEVAE EAQSGGD

Data sets:
Data typeCount
13C chemical shifts364
15N chemical shifts125
1H chemical shifts125

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1gamma-synuclein monomer1

Entities:

Entity 1, gamma-synuclein monomer 127 residues - Formula weight is not available

1   METASPVALPHELYSLYSGLYPHESERILE
2   ALALYSGLUGLYVALVALGLYALAVALGLU
3   LYSTHRLYSGLNGLYVALTHRGLUALAALA
4   GLULYSTHRLYSGLUGLYVALMETTYRVAL
5   GLYALALYSTHRLYSGLUASNVALVALGLN
6   SERVALTHRSERVALALAGLULYSTHRLYS
7   GLUGLNALAASNALAVALSERGLUALAVAL
8   VALSERSERVALASNTHRVALALATHRLYS
9   THRVALGLUGLUALAGLUASNILEALAVAL
10   THRSERGLYVALVALARGLYSGLUASPLEU
11   ARGPROSERALAPROGLNGLNGLUGLYGLU
12   ALASERLYSGLULYSGLUGLUVALALAGLU
13   GLUALAGLNSERGLYGLYASP

Samples:

sample_1: gamma-synuclein, [U-13C; U-15N], 0.35 mM; NaCl 137 mM; KCl 2.7 mM; Na2HPO4 10 mM; K2HPO4 2.4 mM; D20 10%

conditions_1: pH: 7.4; temperature: 278 K

Experiments:

NameSampleSample stateSample conditions
HNCACBsample_1not availableconditions_1
HNCOsample_1not availableconditions_1

Software:

No software information available

NMR spectrometers:

  • Varian INOVA 800 MHz

Related Database Links:

DBJ BAD97087 BAG35077 BAG73792
EMBL CAG46587 CAG46589
GB AAB64109 AAC27738 AAC36550 AAC36586 AAH14098
REF NP_003078 XP_002820773 XP_003828245 XP_003951754 XP_004049763
SP O76070