BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 4824

Title: Conformations of the Regulatory Domain of Cardiac Troponin C Examined by Residual Dipolar Couplings; Complex with peptide

Authors: Paakkonen, Kimmo; Sorsa, Tia; Drakenberg, Torbjorn; Pollesello, Piero; Tilgmann, Carola; Permi, Perttu; Heikkinen, Sami; Kilpelainen, Ilkka; Annila, Arto

Citation: Paakkonen, Kimmo; Sorsa, Tia; Drakenberg, Torbjorn; Pollesello, Piero; Tilgmann, Carola; Permi, Perttu; Heikkinen, Sami; Kilpelainen, Ilkka; Annila, Arto. "Conformations of the Regulatory Domain of Cardiac Troponin C Examined by Residual Dipolar Couplings"  Eur. J. Biochem. 267, 6665-6672 (2000).

Assembly members:
Troponin C, polymer, 93 residues, Formula weight is not available
TnI peptide, polymer, 26 residues, Formula weight is not available

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
Troponin C: GSMDDIYKAAVEQLTEEQKN EFKAAFDIFVLGAEDGCIST KELGKVMRMLGQNPTPEELQ EMIDEVDEDGSGTVDFDEFL VMMVRCMKDDSKG
TnI peptide: RISADAMMQALLGARAKESL DLRAHL

Data sets:
Data typeCount
residual dipolar couplings52

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1TnC1
2TnI2

Entities:

Entity 1, TnC 93 residues - Formula weight is not available

1   GLYSERMETASPASPILETYRLYSALAALA
2   VALGLUGLNLEUTHRGLUGLUGLNLYSASN
3   GLUPHELYSALAALAPHEASPILEPHEVAL
4   LEUGLYALAGLUASPGLYCYSILESERTHR
5   LYSGLULEUGLYLYSVALMETARGMETLEU
6   GLYGLNASNPROTHRPROGLUGLULEUGLN
7   GLUMETILEASPGLUVALASPGLUASPGLY
8   SERGLYTHRVALASPPHEASPGLUPHELEU
9   VALMETMETVALARGCYSMETLYSASPASP
10   SERLYSGLY

Entity 2, TnI 26 residues - Formula weight is not available

1   ARGILESERALAASPALAMETMETGLNALA
2   LEULEUGLYALAARGALALYSGLUSERLEU
3   ASPLEUARGALAHISLEU

Samples:

sample_1: Troponin C mM; TnI peptide mM

cond1: pH: 6.0; temperature: 303 K

Experiments:

NameSampleSample stateSample conditions
not availablesample_1not availablecond1

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Related Database Links:

BMRB 17103 25034 25035 5386
PDB
DBJ BAD97171
EMBL CAA38102 CAA62301 CAG46782 CAH92121
GB AAA16157 AAH96165 AAH96166 AAH96167 AAH99631
PRF 1616225A
REF NP_000354 NP_001126240 XP_001085820 XP_001381826 XP_002829813
SP P19429