BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 20024

Title: NMR solution structure of mu-conotoxin TIIIA   PubMed: 17142296

Authors: Lewis, Richard; Schroeder, Christina

Citation: Lewis, Richard; Schroeder, Christina; Ekberg, Jenny; Nielsen, Katherine; Loughnan, Marion; Thomas, Linda; Adams, Denise; Drinkwater, Roger; Adams, David; Alewood, Paul. "Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels"  Mol. Pharmacol. 71, 676-685 (2007).

Assembly members:
TIIIA, polymer, 22 residues, 2471.881 Da.

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):
TIIIA: RHGCCKGXKGCSSRECRXQH CC

Data sets:
Data typeCount
conformer coordinate sets1

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1TIIIA1

Entities:

Entity 1, TIIIA 22 residues - 2471.881 Da.

1   ARGHISGLYCYSCYSLYSGLYHYPLYSGLY
2   CYSSERSERARGGLUCYSARGHYPGLNHIS
3   CYSCYS

Samples:

sample_1: TIIIA 2 mM

sample_2: TIIIA 2 mM

sample_conditions_1: pH: 3; temperature: 286.5 K

sample_conditions_2: pH: 3; temperature: 286.5 K

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_2isotropicsample_conditions_2
2D 1H-1H NOESYsample_2isotropicsample_conditions_2
2D 1H-1H COSYsample_2isotropicsample_conditions_2

Software:

UXNMR, Bruker Biospin - collection

NMR spectrometers:

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