BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
Member of WWPDB

BMRB Entry 16595

Title: HIV Fusion Peptide in Cholesterol-Rich Membranes   PubMed: 18370385

Authors: Weliky, David

Citation: Qiang, Wei; Bodner, Michele; Weliky, David. "Solid-state NMR Spectroscopy of human immunodeficiency virus fusion peptides associated with host-cell-like membranes: 2D correlation spectra and distance measurements support a fully extended conformation and models for specific antiparallel strand registries"  J. Am. Chem. Soc. 130, 5459-5471 (2008).

Assembly members:
HIV_Fusion_Peptide, polymer, 31 residues, Formula weight is not available

Natural source:   Common Name: HIV   Taxonomy ID: 12721   Superkingdom: virus   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
HIV_Fusion_Peptide: AVGIGALFLGFLGAAGSAMG ARSCKKKKKKW

Data sets:
Data typeCount
13C chemical shifts70

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1HIV Fusion Peptide1

Entities:

Entity 1, HIV Fusion Peptide 31 residues - Formula weight is not available

1   ALAVALGLYILEGLYALALEUPHELEUGLY
2   PHELEUGLYALAALAGLYSERALAMETGLY
3   ALAARGSERCYSLYSLYSLYSLYSLYSLYS
4   TRP

Samples:

sample_1: HIV Fusion Peptide, [U-99% 13C; U-99% 15N], 20 mM; Membrane 750 mM; HEPES 5 mM; H2O 95%; D2O 5%

sample_conditions_1: ionic strength: 3 mM; pH: 7.0; pressure: 1 atm; temperature: 223 K

Experiments:

NameSampleSample stateSample conditions
2D 13C-13C spin diffusionsample_1solidsample_conditions_1

Software:

NMRPipe, Cornilescu, Delaglio and Bax, Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax - processing

NMR spectrometers:

  • Varian Infinity Plus 400 MHz

Related Database Links:

GB AAB68317 AAB68318 AAB68319 AAB68320 AAB68321